The monograph by Novoselov V.M., Krut’ko V.N., Dontsov V.I. Fundamentals of Gerontology: Physician’s Pocket Guide has been published. Moscow: Eksmo. 2024. – 352 p.

December 21, 2024.

This manual is a guide in the daily practical work of a gerontologist. Information on genetics, physiology, biochemistry of aging, algorithms for diagnosing aging, factors of preventing aging and age-related diseases, presented in a concise form, will serve as an important aid in the work of a doctor.

The Proceedings of the ISA RAS published an article by V.N. Krut’ko, N.S. Potemkina. Can the EAT–Lancet Planetary Diet for Health Ensure Sustainable Nutrition?

August 2024

The paper analyzes the EAT–Lancet diet, which is widely discussed in the scientific literature and is positioned as a sustainable planetary diet. At the same time, the sustainability of this diet (diet) is questioned in a number of studies, and attempts are made to improve individual aspects of the diet, which do not lead to an increase in its sustainability as a whole. Our analysis of the EAT–Lancet diet in terms of nutrient adequacy showed that it can be complete if sprouted grains are included in its composition. Such aspects of the diet sustainability as preventive focus, environmental safety, availability and acceptability are considered. A reasonable assumption is made that the use of various sprouted grains and microgreens within this diet can provide the EAT–Lancet diet with such qualities as a health and preventive focus, environmental safety and availability.

Text of the article (Proceedings of the Institute of Informatics of the Russian Academy of Sciences. Vol. 74. 4/2024. P.64-74. DOI: 10.14357/20790279240408 EDN: AMXGLV)

The monograph by Dontsov V.I., Krut’ko V.N. has been published. Anti-aging therapy for everyone: What is aging and how to fight it. M.: LENAND, 2024. – 248 p.

July 14, 2024.

A new area of ​​modern medicine – “Anti-Ageing Medicine” (Anti-aging medicine, Aging prevention) combines deep fundamental research in biomedicine and the broad preventive capabilities of practical medicine, as well as modern general health and cosmetology technologies.

Written by Russian authors who have worked for many years in the field of aging biology, preventive and health medicine, this book is a unique guide in this rapidly developing field of science and practice, opening up fundamentally new possibilities for influencing the deep mechanisms and consequences of human aging.

The reduction in the rate of human aging in the 20th century as a result of improved quality of life and the effectiveness of health care.

March 2024.

The report by V.I. Dontsov, V.N. Krut’ko was presented at the XI All-Russian scientific and practical conference with international participation “Population Health and Quality of Life”.
A decrease in the aging rate has been observed for populations of all developed countries of the world since the mid-20th century. Correlation analysis of the relationship between the degree of decrease in the aging rate and the characteristics of living conditions showed that the highest correlation for all ages is observed with the effectiveness of health care in the country. The aging rate calculated based on the increase in mortality intensity decreases on average by 1.5 - 2.0 times by 2000 compared to 1950-60. The most likely reason is the undoubted significant improvement in medical and social care and quality of life since the mid-20th century, primarily the success of preventive medicine in the treatment of chronic age-related diseases.

Therapy for chronic diseases can directly affect the mechanisms of aging itself (syndromes common to aging and chronic diseases). The results obtained open the possibility of influencing the aging rate, which was previously considered unlikely.

The Proceedings of the ISA RAS Published an Article by V.N. Krut’ko Life Expectancy as an Indicator of the Quality of Government

March 2024

The paper analyzes the possibilities of using the life expectancy indicator (LE) as an indicator of the macroeconomic and psychological situation in the country, as well as an indicator of the quality of government. The analysis is based on data on changes in LE in Russia in the 20th and 21st centuries. A comparison is made with similar data for Sweden. It is shown that LE very quickly and sensitively reflects these characteristics and can be used to assess them.

TASS Science:
A digital platform in the Russian Federation has created recommendations for supporting health based on 35 million articles by doctors

March 26, 2024.

MOSCOW, March 26. /TASS/. A consortium of leading scientific groups, including specialists from the BIKAD project, has created a digital platform that uses data from more than 35 million publications in international and Russian scientific journals to create recommendations for users on maintaining and improving health.

The database, which the system was equipped with at the beginning of 2024, includes articles on all areas of medicine, including clinical, preventive, as well as publications in the field of pharmacology. The digitized scientific and methodological knowledge base serves as the basis for services that offer the user a step-by-step plan for adjusting nutrition, activity, psychological exercises and lifestyle in general to improve the quality of life and active longevity.

November 09, 2023.

The report presented the results of R&D and implementation of the project's developments achieved by the project in 2020-2023.

Excerpt from the resolution of the Bureau of the Section of Preventive Medicine of the Department of Medical Sciences of the Russian Academy of Sciences:
The presented report demonstrated the high scientific and applied significance of the Project. The R & D conducted within the framework of the Project relate to advanced methods of analysis and management of health and quality of life, the methodological foundation of which is created by preventive medicine and hygiene. The proposed information technologies can be widely used in health protection, preventive medicine, hygiene, prevention of non-communicable diseases and a number of other areas aimed at improving the quality of life of people. The presented review of the developed services and the effects of their implementation are a good illustration of the practical feasibility, importance and demand for this area. Receiving financial support for the Project from the National Technological Initiative emphasizes the relevance and significance of the project at the national level. The Bureau of the Section of Preventive Medicine of the Department of Medical Sciences of the Russian Academy of Sciences has resolved:
Approve the direction of activity and the results obtained.

Recommend to Sechenov University (Institute of Public Health, Departments of General Hygiene and Sports Medicine), Federal Research Center "Informatics and Management" of the Russian Academy of Sciences, OOO "Soyuz Sport i Zdorovie", as well as to the Project leaders - Krut’ko V.N., Mitrokhin O.V., Deminov M.M.:

• continue research and development..., focusing on expanding the range of organizations and departments into whose practical activities the results can be implemented;
• inform the Ministry of Health, the Ministry of Science and Higher Education, as well as other government agencies whose interests and activities include issues of health preservation and improving the quality of life about the possibilities for the beneficial use of the results;
• taking into account the high social significance and economic efficiency of the technologies developed in the Project, recommend their transfer to large state, regional and corporate digital platforms, primarily EMIAS/EGIZS;
• consider the use of technologies created within the framework of the project in the field of gerontology to be a significant and support-worthy direction for testing promising means of preventing aging.

The project team, together with MIPT, prepared the chapter “Risk Forecasting Tools Based on the Collected Information for Two Types of Occupational Diseases” in the book “Artificial Intelligence for Healthy Longevity” published by Springer (2023)

July 2023.

Annotation. The article represents the construction of algorithms for monitoring and predicting the risk of occupational diseases (sensorineural hearing loss and vibration disease from exposure to local and general vibration) and the use of data from clinical and instrumental examination of patients.

The project team prepared an article "Internet system for automated management of personal health, working capacity and quality of life", authors V.N.Krut’ko, V.I.Dontsov, M.M.Deminov. The article was published in the journal "Information Technologies and Computing Systems" 2/2023

June 2023.

Annotation. The paper presents a new developed method and an Internet system implementing it for automated assessment and correction of health, performance, and quality of life. These processes are 100% autonomous and automatic. A smartphone application, LifestyleAssistant, has been created, which is the user and system interface. This application is integrated with a cloud server that analyzes data and automatically generates correction recommendations. The system is based on the automated collection and comprehensive analysis of multimodal data on human health, lifestyle, quality of life, priorities, and habitat. Based on these data, the system automatically generates personalized recommendations for correction of detected problems in health, performance, and quality of life, and monitors the effectiveness of the personal correction program. Keywords: information and analytical system, data processing platform, smartphone application, health management, performance management, quality of life management.

The article was prepared with the support of NTI, the HealthNet roadmap.

The project team has prepared an article "Assessment of the rate of population aging for assessing personal potential and quality of life", authors V.I.Dontsov, V.N.Krut’ko. The article was published in the proceedings of the XVI international scientific conference "System Analysis in Medicine" (October 13-14, 2022, Blagoveshchensk)

October 14, 2022.

Annotation. In general, the level of labor and social activity of a person, his quality of life (QOL) and personal potential (PP) depend on his general viability, which decreases with age. It is shown that the rate of aging for the countries considered has remained unchanged for centuries, but since the middle of the twentieth century there has been a constant decrease in the rate of aging, which counteracts the demographic effect of population aging.

The article was prepared with the support of NTI, the HealthNet roadmap.

The project team has prepared an article entitled “Comparative Analysis of Methods for Assessing the Rate of Population Aging”, authors V.I.Dontsov, V.N.Krut’ko * , N.A.Ermakova. The article has been accepted for publication in the journal "Biophysics"

September 14, 2022.

Annotation. The essence of aging is the decline in overall vitality with age, which is the main characteristic of a person's personal potential. Vitality (v) is determined as the probability of remaining alive for a year, mortality (m) is defined as the probability to die within a year and is accordingly opposite in meaning, but adequate in the sense of an indicator that determines the degree of aging of the organism. For quantitative The Gompertz-Makeham formula (traditional) has long been widely used in aging analysis approach), which describes quite well the phenomenon of exponential growth of mortality with age. Another approach to assessing the aging process is to calculate the rate of growth the intensity of mortality with age (d(m)), which characterizes the rate of aging. The aim of the work is a comparison of the information content, accuracy and convenience of these approaches for solving the problem estimates of the rate of human aging based on the analysis of age-related mortality in humans populations. It is shown that the indicator d(m) is the most accurate, simple to calculate, mathematically and biologically adequate indicator of the rate of aging. Its use allows us to assess historical changes in the characteristics of human population aging: the constancy of the rate of aging in history and a decrease since the mid-20th century for middle and old age ages, as well as maintaining a reduced rate of aging for long-livers.

The article was prepared with the support of NTI, the HealthNet roadmap.

The project team has prepared an article entitled “A Method for Optimizing the Assessment of Human Biological Age as an Integral Characteristic of Human Potential,” by V. I. Dontsov, V. N. Krut’ko, and E. V. Belovoy. The article has been accepted for publication in the journal “Proceedings of the Institute of Systems Analysis of the Russian Academy of Sciences.”

May 11, 2022.

Annotation. The basis of economic well-being and development of any country is the personal potential (LP) of a person, which includes physiological, subject-material and social resources. The basic component of LP is its physical (physiological) component, which is understood as the ability of an individual to perform physical and intellectual work. An integral characteristic of this component is general viability, which naturally and sharply decreases with age in the process of biological aging, and the quantitative assessment of which is the mortality rate for populations, and for an individual - biological age (BA). Therefore, the assessment of a person's BA is one of the most important tasks in the range of problems of studying the age dynamics of LP. The authors have developed a method and a computer system for optimizing biomarkers (BM) to determine a person's BB, taking into account customizable BM selection criteria. The method allows automating the construction of BM panels, increasing the accuracy of BM determination and reducing the number of measured BM to the necessary and sufficient optimum.

The article was prepared with the support of NTI, the HealthNet roadmap.

The National Healthcare Journal published an article entitled “Health and Quality of Life Management Issues: The Intelligent Digital Platform “Health Heuristics”

April 2022.

Annotation: The article considers a number of health and quality of life management issues, such as motivating people to a healthy lifestyle (HLS) using gamification and monetization methods, validity of recommendations and their personalization, monitoring results and supporting the use of health-preserving programs, correct orientation in the context of a huge amount of unreliable information on health improvement methods from the Internet, etc. The tool for solving these problems is an intelligent digital platform created by the authors, which, based on big data about the human body, lifestyle and habitat, automatically generates personalized recommendations for a healthy lifestyle aimed at improving health indicators and quality of life. A set of scientific, methodological, technological, regulatory, legal, motivational, commercial and other approaches and solutions developed within the framework of this project is considered. A comparative analysis of a number of platform analogues was carried out. Key words: digital health profile; digital platform; health preservation; healthy lifestyle; Internet technologies; preventive medicine; personalized medicine; quality of life management

For citation : Krut’ko V.N., Deminov M.M., Briko N.I., Mitrokhin O.V., Chichua D.T. Problems of health and quality of life management: the intelligent digital platform "Health Heuristics". National Health. 2021; 2 (2): 51–58. https://doi.org/10.47093/2713-069X.2021.2.2.51-58

Scientific director of the Health Heuristics project, Professor V.N. Krut’ko gave a plenary report “Information technologies for optimizing active longevity programs” at the scientific and practical conference “Modern aspects of active longevity”

April 14, 2022.

The conference "Modern aspects of active longevity" is organized by the Ministry of Health of the Moscow Region (MOH); State Budgetary Healthcare Institution of the Moscow Region MONIKI named after M.F. Vladimirsky (MONIKI); Federal State Budgetary Scientific Institution "National Research Institute of Public Health named after N.A. Semashko".

The processing of the results of the experiment on practical collection of physiological indicators has been completed. A set of methods has been prepared, ready for transfer to interested specialized teams of universities.

March 2022.

The processing of the results of the experiment on practical collection of physiological indicators related to physical activity, the state of the cardiovascular system, sleep and rest patterns, nutrition parameters, sleep and emotional state has been completed. Based on the results of the experiment processing, the BIKAD project team confirmed a number of hypotheses that are fundamentally important for building decision support systems in the field of active longevity.

An article entitled “A set of food products for preventing muscle mass loss and preventing chronic non-communicable diseases in old age” has been prepared and sent to the journal “Healthcare of the Russian Federation”.

February 2022.

The scientific director of the project, Professor V.N. Krut’ko, and his colleagues managed to create the best of the known diets in terms of meeting the requirements of balance, deficiency-free, availability and compliance with official preventive dietary recommendations available in the literature. Half-jokingly, I would like to announce a “challenge” - i.e. a challenge - “Who can offer a better diet than us?” But seriously, we think it is worth publishing our article from the point of view of its practical usefulness, since it offers a specific unique diet created by us, the best for solving the most important task of preventing chronic non-communicable diseases and loss of muscle mass. It turns out that the “programmed micronutrient deficiency” postulated by leading nutritionists can be overcome with the help of modern methods of mathematical programming.

Wash Out the Virus: Scientist Gives Simple Tips on How to Avoid a Cold

November 2021.

Strengthening the immune system and taking preventive measures will help avoid catching a cold. If a person starts to get sick, then for a speedy recovery it is necessary to follow a number of recommendations. The project manager Vyacheslav Nikolaevich Krut’ko spoke with Vechernyaya Moskva about proper hardening of the body, effective elimination of the virus with the help of ordinary salt, as well as ways to protect household members.